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Chemotherapy-Induced Peripheral Neuropathy: New Perspectives From the Bedside to the Bench
Charles L. Loprinzi, MDChemotherapy-induced peripheral neuropathy (CIPN) is a significant, debilitating complication of chemotherapy administration for cancer.
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Update on Drug Therapy for Neuropathic Pain in the Medically Ill
Russell K. Portenoy, MD -
Pain & Aging: 3rd Annual Perry Fine Lecture at West Virginia University
Perry Fine, MDAs the population ages, more individuals will be living with chronic pain, resulting in increased morbidity, mortality, and healthcare utilization.
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Pain Quality Predicts Lidocaine Analgesia among Patients with Suspected Neuropathic Pain
Ian R. Carroll, MD, MSThe expression and modulation of voltage-gated sodium channels are known to contribute to various animal models of neuropathic pain.
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Management of Headache in the Elderly
Matthew S. Robbins, MDDiagnosis and management of headache can be challenging in older patients. New-onset headache is rare in this population and is usually a symptom of another disorder.
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EFNS guidelines on the pharmacological treatment of neuropathic pain: 2009 revision
Nadine Attal, MD, PhDInitiated or caused by a primary lesion or dysfunction in the nervous system, neuropathic pain is a manifestation of multiple, heterogeneous disorders.
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The War on Cancer Pain: New Battles
Judith A. Paice, PhD, RNMore effective surgical, chemotherapeutic, and radiologic therapies for cancer have increased overall survival rates.
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The Effects of Pregabalin on Sleep Disturbance Symptoms Among Individuals with Fibromyalgia Syndrome
I. Jon Russell, MD, PhDIn addition to pain, patients with fibromyalgia often report sleep disturbances. Studies have shown that abnormal sleep patterns in fibromyalgia are characterized by delayed onset, decreased efficiency, and reduced slow wave and rapid eye...
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Neuropathic Pain in HIV Disease
David M. Simpson, MDPeripheral neuropathy is one of the most common neurologic complications of HIV. In fact, nearly 50% of HIV patients are thought have signs of neuropathy, with increased risk in those with advanced disease.
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Sodium Channel Expression in Keratinocytes: Implications for Neuropathic Pain
Frank L. Rice, PhDSodium channels are primary determinants of membrane excitability. Interestingly, recent evidence suggests that keratinocytes in the skin express voltage-gated sodium channels, with increased levels observed in such neuropathic pain conditions...






